Mailing Address:
Harvard Medical School
Department of Ambulatory Care and Prevention
133 Brookline Avenue, 6th Floor
Boston, MA 02215

Email: Grace_Lee@harvardpilgrim.org

Phone: (617) 509-9959
Fax: (617) 859-8112

Staff Assistant: Pamela Butler

Affiliations:
Children's Hosptial Boston

Websites:
Center for Child Health Care Studies

Grace Lee, MD, MPH

My overall research agenda is focused on vaccine economics, safety and policy. My prior work has focused on using decision analytic models and cost-effectiveness analysis to guide national decision-making regarding vaccine use. I also lead research on the impact of limitations in vaccine financing on the ability of underinsured children to receive vaccines in the U.S. Understanding the important role of the current vaccine financing system has led us to identify potential mechanisms for increasing delivery of vaccines to vulnerable children. Furthermore, I am currently studying influenza vaccine financing in the U.S. for children and adults to identify potential mechanisms to optimize the delivery of flu vaccine, particularly as universal recommendations continue to expand.

I also lead a group of activities within the Vaccine Safety Datalink project, which is a collaboration among 7 large HMOs in the U.S., focused on influenza vaccine safety. These activities are currently focused on studying the safety of both inactivated and live attenuated influenza vaccines using new statistical methods to rapidly detect signals in real-time. Our experience studying seasonal vaccine will prepare us to be able to rapidly study the safety of a pandemic influenza vaccine, if one should be deployed in the population in the future.

1. Lee GM, Salomon JA, Friedman JF, Hibberd PL, Ross-Degnan D, Zasloff E, Bediako S, Goldmann DA. Illness Transmission in the Home: A Possible Role for Alcohol-Based Hand Gels. Pediatrics 2005;115:852-860.
2. Lee GM, Lett S, Schauer S, LeBaron CW, Murphy TV, Rusinak D, Lieu TA, for the Massachusetts Pertussis Study Group. Societal costs and morbidity of pertussis in adolescents and adults. Clin Infect Dis 2004;39:1572-1580.
3. Lee GM, LeBaron CW, Murphy TV, Lett S, Schauer S, Lieu TA. Pertussis among adolescents and adults: Should we vaccinate? Pediatrics 2005; 115:1675-1684.
4. Lee GM, Gortmaker SL, McIntosh K, Hughes MD, Oleske JM, for the PACTG 219C Team. Quality of Life in HIV-Infected Children. Pediatrics 2006; 117: 273-83.
5. Lee GM, Santoli JM, Hannan C, Messonier ML, Sabin JE, Rusinak D, Gay C, Lett SM, Lieu TA. Gaps in Vaccine Financing for Underinsured Children in the United States. JAMA 2007; 298(6): 638-643.
6. Pfoh E, Wessels MR, Goldmann DA, Lee GM. Burden and Economic Cost of Group A Streptococcal Pharyngitis. Pediatrics, 2008; 121: 229-234.
7. Lee GM, Lorick S, Pfoh E, Kleinman K, Fishbein D. Adolescent Immunizations: Missed Opportunities for Prevention. Pediatrics, in press.
8. Nakamura MM, Lee GM. Influenza Vaccination in Adolescents with High-Risk Conditions. Pediatrics, in press.